Insights into Proteomics Reveal Mechanisms of Ethanol-Enhanced Bacterial Cellulose Biosynthesis by Komagataeibacter nataicola

Nata de coco, known as bacterial cellulose (BC), has been given much attention in the food industry and biomaterial areas due to its specific properties such low calorie content, high content of fiber, purity biocompatibility. Komagataeibacter spp. are indispensable microorganisms for BC production their highly efficient production. Here, proteomics was applied investigate metabolism regulation mechanisms yield improvements K. nataicola Y19 by 48 ± 3% after ethanol supplementation. The results evidenced that differentially expressed proteins involved biosynthesis system, glycolytic pathway, TCA cycle oxidative phosphorylation process were up-regulated. accelerated providing more energy via intermediate metabolites. Furthermore, elongation factor Tu, chaperone DnaK translocase subunit SecB may be synthesis procedure regulating electron transfer, hydrolysis ATP protein transformation. Moreover, ethanol-enhanced associated with decreased expression endoglucanase. This research elucidates mechanism higher based on addition, references nata coco efficiency synthetic future.